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KMID : 0378019740170040549
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New Medical Journal
1974 Volume.17 No. 4 p.549 ~ p.554
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Toxic Reactions of Epinephrine Overdose
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Abstract
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Accidentally or carelessly given epinephrine overdose is dangerous and cause even death. Subarachnoid hemorrhage and hemiplegia have been reported in man on many literatures following as little as 0.5 mg of epinephrine injection.
And also, increased risk of arrhythmias was well recognized when epinephrine injection was used during inhalation anesthesia with halogenated hydrocarbons.
In these cases presentations, about 1 mg and 2 mg of epinephrine were given carelessly.
Toxic reactions of epinephrine were noticed and immediate treatment were started with intravenous
rapid acting barbiturate together with halothane-oxygen anesthesia and hyperventilation. All three cases were uneventfully recovered.
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